CH−π “T-Shape” Interaction with Histidine Explains Binding of Aromatic Galactosides to Pseudomonas aeruginosa Lectin LecA
نویسندگان
چکیده
منابع مشابه
Potent divalent inhibitors with rigid glucose click spacers for Pseudomonas aeruginosa lectin LecA.
The synthesis of a new rigid spacer based on carbohydrate-triazole repeating units and their incorporation into divalent systems is described. Inhibition studies showed that a well-matched system with a rigid spacer with flexible ends leads to the most potent inhibition of Pseudomonas aeruginosa lectin LecA.
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ژورنال
عنوان ژورنال: ACS Chemical Biology
سال: 2013
ISSN: 1554-8929,1554-8937
DOI: 10.1021/cb400303w